Primary Ciliary Dyskinesia (PCD)

PCD is an inherited disorder causing defects of motile (moving) cilia. Motile cilia are needed to keep your lungs, sinuses, and ears free of organisms and debris that can cause infection and disease. A person with PCD experiences chronic, recurrent infections in the...

Alpha-1 Antitrypsin Deficiency

Alpha-1 Antitrypsin Deficiency is a genetic disorder caused by defective production of a protein called Alpha-1 antitrypsin, causing decreased activity of the protein in the lungs and a buildup of the protein in the liver, which can cause serious damage to both...

Cystic fibrosis (CF)

Cystic Fibrosis (CF) is a genetic disease. While it affects the whole body, it has the worst impact on the lungs and digestive system. The defective gene produces an abnormal CFTR (cystic fibrosis transmembrane conductance regulator protein). In the airway this...

Gram-negative infections

Gram-negative bacteria are a group of germs that can cause respiratory infections. Bronchiectasis patients are particularly susceptible to gram-negative infections, and many get infected with Pseudomonas aeruginosa. Other species of gram-negative bacteria that...